ABSTRACT
PURPOSE: The aim of this study was to investigate differences between virus-associated necrotizing enterocolitis (V+NEC) and non-virus necrotizing enterocolitis (V-NEC). METHODS: We reviewed the medical records of 86 neonates with NEC who were admitted to the neonatal intensive care unit (NICU) of Inje University Sanggye Paik hospital from July 1st, 1999 to June 30th, 2009. We divided patients into V+NEC group (n=22) and V-NEC group (n=64). We analyzed retrospectively the differences of predisposing factors, clinical characteristics, laboratory findings and radiological findings between two groups. RESULTS: The rate of vaginal delivery in V+NEC group was higher than V-NEC group (P=0.026). The rate of abdominal distension in V+NEC was lower than V-NEC group (P=0.019). There were no differences of predisposing factors, clinical characteristics, laboratory findings and radiological findings, disease severity, having an operation and mortality except above two factors between V+NEC group and V-NEC group. CONCLUSION: There were no differences of general characteristics, disease severity, operation rate and mortality between V+NEC group and V-NEC group.